Chiasma is focused on improving the lives of patients who face challenges associated with their existing treatments for rare and serious chronic diseases. Employing its Transient Permeability Enhancer (TPE®) technology platform, Chiasma seeks to develop oral medications that are currently available only as injections. In July 2019, the Company reported positive top-line data from its completed Phase 3 clinical trial of its octreotide capsules product candidate, conditionally trade named MYCAPSSA, for the maintenance therapy of adult patients with acromegaly. In January 2020, the FDA accepted for review the resubmission of Chiasma’s New Drug Application seeking marketing approval for MYCAPSSA in the United States and assigned PDUFA action date of June 26, 2020. The Company is also currently conducting a Phase 3 multinational clinical study designed for EMA commercial approval.  Chiasma is headquartered in Needham, MA with a wholly owned Israeli subsidiary.

The Regional Business Director position is an exciting opportunity to help build Chiasma’s very first sales organization and contribute to the successful launch of Chiasma’s first product. Initially the Regional Business Director will be tasked with establishing the Chiasma sales culture by recruiting and hiring our first group of Territory Business Managers who will act as the key interface between Chiasma and the external market. Ongoing, the primary objective of the Regional Business Director is to ensure the attainment of sales objectives by maximizing the effectiveness and productivity of the Territory Business Managers.  Regional Business Directors are responsible to oversee the implementation of the national sales strategy by providing direction, oversight and guidance to the Territory Business Managers, ensuring that they have the necessary resources and skills to impact utilization in favor of Chiasma’s product.  This involves a significant amount of time spent coaching and developing individuals through regularly scheduled field visits, as well as ensuring that representatives are receiving the appropriate amount of training.  It is the Regional Business Director’s responsibility during field visits with Territory Business Managers to work collaboratively to implement the annual territory plan, troubleshoot challenging customer situations, and ensure that all necessary skills are being employed to impact the sale of specific products in our designated therapeutic categories.

As the first line management job within Sales at Chiasma, Regional Business Directors act as liaisons between field sales and the various internal departments whose work impacts or is impacted by field activity. As a conduit of information to and from the field, Regional Business Directors must facilitate Territory Business Manager recognition and understanding of how changes in the industry or within Chiasma affect their approach to selling. As a way of maintaining high motivation and commitment from the sales team, the Regional Business Director must at times act to transfer information from corporate, translating it into terms that can be easily understood and accepted.


  • Responsible for meeting or exceeding sales goals in a defined market through the appropriate utilization and deployment of available resources.

  • Maintains a working knowledge of environmental and industry factors influencing product utilization in the Region (e.g., managed care, teaching institutions, medical societies).

  • Identifies business opportunities through analysis of customers and trends within the Region and communicates this information to Territory Business Managers and management.

  • Partners with peer directors to uncover Regional business opportunities and plan team sales initiatives.

  • Reviews Region sales data to monitor individual and group performance against objectives; uses data as a foundation for the allocation of effort and resources to impact the business and takes corrective action as necessary to ensure metrics and objectives are met.

  • Provides clear and timely direction to Region on broader Chiasma business objectives and national sales strategies, and the implications for the goals of the Region. Uses such information as foundation for working with Territory Business Managers to establish realistic but challenging goals at the individual level.

  • Conducts field coaching interactions with Territory Business Managers, providing them with regular constructive feedback about their performance (against predetermined objectives) and development needs.  Prioritizes time and effort based on specific circumstances and business needs.

  • Strategically manages the Chiasma Performance Management process to insure proper and equitable development and compensation of team members.

  • Serves as an active member of the national management team by sharing best practices, creating new approaches to the marketing of our products and contributing ideas to the business planning process.

  • Ensures the timely and accurate completion of all territory and Region level administrative tasks, including; expense reporting, program funding requests and management communications.


  • Bachelor’s Degree in a business or scientific discipline required, MBA or advanced scientific degree preferred

  • Minimum of 8 years of strong results-oriented pharmaceutical sales experience.  3 of those years' minimum managing other sales reps.

  • Candidates must demonstrate a consistent track record of success (Top 20% performance). President’s Club or other top tier awards preferred.

  • Experience selling into the acromegaly market, endocrinology, rare disease and/or specialty sales experience, as well as selling into hospital systems strongly preferred

  • Complex sales model and experience selling into a competitive market is a requirement.

  • Experience launching a new product is a plus.

  • Demonstrated success at strategic territory management.

Chiasma Inc. (the "Company") is an equal opportunity employer.  All qualified applicants will be considered without regard to age, race, color, sex, religion/creed, national origin, marital status, ancestry, citizenship, military, reservist or veteran status, pregnancy, sexual orientation or preference, gender identity, gender expression, physical or mental disability, genetic predisposition or carrier status, or any other category protected under applicable federal, state or local law.  Consistent with its obligations under applicable law, the Company will make reasonable accommodations for qualified individuals with disabilities.  If you require an accommodation in the application process, please contact a member of the Company’s Human Resources department.